May 19, 2022
Melatonin may offer a sleep benefit in higher doses.
"Researchers from Brigham and Women’s Hospital conducted the study in 24 healthy, older adults to evaluate whether a high-dose or a low-dose melatonin supplement could improve sleep. The team found that the higher dose had a significant impact, increasing total sleep time compared to placebo by more than 15 minutes for nighttime sleep and by half an hour for daytime sleep. Results are published in The Journal of Pineal Research" reports The Harvard Gazette.
"The authors note that their study will need to be replicated in larger trials and with other doses of melatonin to determine whether a dose between 0.3 and 5 mg may work as well. The study did not include participants who had a significant sleep disorder and the study’s findings may not be applicable to people who do. "